Effect of Manuka honey administration on malondialdehyde, in intense exercise

Authors: Ramona Jurcău1, Ioana Jurcău2

Affiliation: 1 Pathophysiology Department, Faculty of Medicine, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

     2 Clinical Emergency Hospital for Children, Cluj-Napoca, Romania


Background. Honey is known for its many beneficial effects on health, including its antioxidant benefits.

Aims. The objective of the study was to evaluate the effect of Manuka honey (MKH) on malondialdehyde (MDA) in intense exercise.

Methods. 32 healthy volunteer men were randomly assigned to four groups: control (C), who did not receive therapy; and the therapy groups who received MKH before exercise, for: one week (1E=8), two weeks (2E=8), and three weeks (3E=8). For all groups the protocol was the same: short-term intense exercise on a Monark Ergomedic 839E cycle ergometer. MDA was analyzed: 10 min before (T1) and 30 min (T2) and 4h (T3) after the exercise. Statistical evaluation was done using the Student test.

Results. MDA was significantly increased at T2 compared to T1, the most in C and the least in 3E. MDA was significantly reduced in 3E compared to 2E and 1E, at T2 and T3. The biggest difference was between C and 3E, both at T2 and T3.

Conclusions. 1) MKH administration had the same type of effects on MDA, regardless of the administration period. 2) The effects of MKH administered for 3W, 2W and 1W on MDA differed in their intensity at T2 and T3. 3) The MKH action on MDA was most important at T2. 4) Because 3E administration had the most intense and persistent effect on MDA, we recommend it as a modulator of oxidative stress in short-term intense exercise, in sedentary subjects.

Keywords: Manuka honey, malondialdehyde, intense exercise.


Effect of Manuka honey administration on malondialdehyde, in intense exercise